Prompt

Do you have a rapid increase in heart rate upon standing? Are you hypermobile?

Resources

The Embryology, Potential Mechanisms that Tie Together The Pentad

I saw a private lecture from Dr. Maxwell that outlined "Spiky-Leaky Syndrome", an ailment with cyclic cerebrospinal fluid volume increasing and decreasing presenting with Ehlers-Danlos Syndrome, Mast Cell Activation Syndrome, autoimmune disease, dysautonomia, and gastrointestinal dysmotility. These five syndromes/diseases are what Dr. Maxwell is calling "The Pentad" in this lecture.