Ch 14 study guide Mesenchyme (embryonic connective tissue) forms the skeletal system. From where does mesenchyme arise? Most bones are formed from cartilage models. How are ossification centers formed? By when are they formed? What is this process called? What is the other method of bone formation that describes, for instance, how the bones of the cranium develop? From what do the vertebral column and ribs develop? How are vertebrae formed specifically? What parts of the cranium are formed by the neurocranium? Viscerocranium? The appendicular skeleton utilizes what bone formation method? Joints develop from mesenchyme in the developing limbs. What are the three classifications based on tissue type? What are the characteristics of each.